Neurite regrowth stimulation by a red-light spot focused on the neuronal cell soma following blue light-induced retraction.

ABSTRACT: The interaction of light with biological tissues has been considered for various therapeutic applications. Light-induced neurite growth has the potential to be a clinically useful technique for neuron repair. However, most previous studies used either a large illumination area to accelerate overall neurite growth or employed a light spot to guide a growing neurite. It is not clear if optical stimulation can induce the regrowth of a retracted neurite. In the present work, we used blue light (wavelength: 473 nm) to cause neurite retraction, and we proved that using a red-light (wavelength: 650 nm) spot to illuminate the soma near the junction of the retracted neurite could induce neurite regrowth. As a comparison, we found that green light (wavelength 550 nm) had a 62% probability of inducin

SUBMITTER: Kao YC 

PROVIDER: S-EPMC6890775 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature