Reimbursement Status and Recommendations Related to Orphan Drugs in European Countries.

ABSTRACT: Objective: To review the reimbursement recommendations issued by selected European health technology assessment agencies for orphan drugs and the reimbursement status of these drugs; to assess the relationship between the type of recommendation and reimbursement status. Methods: The list of orphan drugs to be included in the analysis was obtained from the European Medicines Agency and Orphanet. Seven European states were included in the analysis: Belgium, England, France, Germany, Poland, Scotland, and Spain. For all identified orphan drugs, relevant data on the reimbursement status and type of recommendation were collected for each country. The relationship between the type of recommendation and reimbursement status was evaluated separately for each considered country, using Cohen's kappa

SUBMITTER: Stawowczyk E 

PROVIDER: S-EPMC6890830 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature