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Venom Diversity and Evolution in the Most Divergent Cone Snail Genus Profundiconus.


ABSTRACT: Profundiconus is the most divergent cone snail genus and its unique phylogenetic position, sister to the rest of the family Conidae, makes it a key taxon for examining venom evolution and diversity. Venom gland and foot transcriptomes of Profundiconus cf. vaubani and Profundiconusneocaledonicus were de novo assembled, annotated, and analyzed for differential expression. One hundred and thirty-seven venom components were identified from P. cf. vaubani and 82 from P. neocaledonicus, with only four shared by both species. The majority of the transcript diversity was composed of putative peptides, including conotoxins, profunditoxins, turripeptides, insulin, and prohormone-4. However, there were also a significant percentage of other puta

SUBMITTER: Fassio G 

PROVIDER: S-EPMC6891753 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature