Single-Molecule hsTnI and Short-Term Risk in Stable Patients With Chest Pain.

ABSTRACT:

Background

Evaluation of stable symptomatic outpatients with suspected coronary artery disease (CAD) may be challenging because they have a wide range of cardiovascular risk. The role of troponin testing to assist clinical decision making in this setting is unexplored.

Objectives

This study sought to evaluate the prognostic meaning of single-molecule counting high-sensitivity troponin I (hsTnI) (normal range <6 ng/l) among outpatients with stable chest symptoms and suspected CAD.

Methods

Participants with available blood samples in PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) were studied, and hsTnI results were analyzed relative to the primary outcome of death, acute myocardial infarction (MI), or hospitalization for unstable angina by

SUBMITTER: Januzzi JL 

PROVIDER: S-EPMC6892172 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature