High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic.

ABSTRACT:

Background

The Sahel region of Chad Republic is a prime candidate for malaria pre-elimination. To facilitate pre-elimination efforts in this region, two populations of Anopheles coluzzii from Central Chad Republic were characterized, their insecticide resistance profile and the possible molecular mechanisms driving the resistance in the field investigated.

Methods

Bloodfed female Anopheles gambiae s.l. resting indoor, were collected at N'djamena and Massakory, Chad in 2018 and characterized for species composition, and infection rate was determined using the TaqMan assay. Susceptibility to various insecticides was assessed using WHO tube bioassays. Cone bioassays were conducted using various long-lasting insecticidal nets (LLINs). Results were analysed using Chi Square test.

SUBMITTER: Ibrahim SS 

PROVIDER: S-EPMC6892245 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature