Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial.

ABSTRACT:

Background

In women with late preterm pre-eclampsia, the optimal time to initiate delivery is unclear because limitation of maternal disease progression needs to be balanced against infant complications. The aim of this trial was to determine whether planned earlier initiation of delivery reduces maternal adverse outcomes without substantial worsening of neonatal or infant outcomes, compared with expectant management (usual care) in women with late preterm pre-eclampsia.

Methods

In this parallel-group, non-masked, multicentre, randomised controlled trial done in 46 maternity units across England and Wales, we compared planned delivery versus expectant management (usual care) with individual randomisation in women with late preterm pre-eclampsia from 34 to less than 37 weeks'

SUBMITTER: Chappell LC 

PROVIDER: S-EPMC6892281 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature