Emergence of the Asian lineage of Zika virus in Angola: an outbreak investigation.

ABSTRACT:

Background

Zika virus infections and suspected microcephaly cases have been reported in Angola since late 2016, but no data are available about the origins, epidemiology, and diversity of the virus. We aimed to investigate the emergence and circulation of Zika virus in Angola.

Methods

Diagnostic samples collected by the Angolan Ministry of Health as part of routine arboviral surveillance were tested by real-time reverse transcription PCR by the Instituto Nacional de Investigação em Saúde (Ministry of Health, Luanda, Angola). To identify further samples positive for Zika virus and appropriate for genomic sequencing, we also tested samples from a 2017 study of people with HIV in Luanda. Portable sequencing was used to generate Angolan Zika virus genome sequences from three peo

SUBMITTER: Hill SC 

PROVIDER: S-EPMC6892302 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature