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Economic Modelling of Chronic Kidney Disease: A Systematic Literature Review to Inform Conceptual Model Design.


ABSTRACT: BACKGROUND:Chronic kidney disease (CKD) is a progressive condition that leads to irreversible damage to the kidneys and is associated with an increased incidence of cardiovascular events and mortality. As novel interventions become available, estimates of economic and clinical outcomes are needed to guide payer reimbursement decisions. OBJECTIVE:The aim of the present study was to systematically review published economic models that simulated long-term outcomes of kidney disease to inform cost-effectiveness evaluations of CKD treatments. METHODS:The review was conducted across four databases (MEDLINE, Embase, the Cochrane library and EconLit) and health technology assessment agency websites. Relevant information on each model was extracted. Transition and mortality rates were also extracte

SUBMITTER: Sugrue DM 

PROVIDER: S-EPMC6892339 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature