Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study.

ABSTRACT:

Background

The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative per-oral carbohydrate load and their influence on tumor characteristics and survival.

Methods

The study setting was on university hospital level with primary and secondary care functions in south-west Norway. Serum and tumor tissue were sampled from a population-based cohort of 60 patients with operable breast cancer who were randomized to either per-oral carbohydrate load (preOp™; n = 25) or standard pre-operative fasting (n = 35) before surgery. Magnetic resonance (MR) metabolomics was performed on serum samples from all patients and high-resolution magic angle

SUBMITTER: Lende TH 

PROVIDER: S-EPMC6894229 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature