Pathways linking combinations of early-life adversities to adult mortality: Tales that vary by gender.

ABSTRACT:

Rationale

Socioeconomic disadvantage, family instability, and abuse are widely studied early-life adversities (ELAs) that may co-occur in the lives of many. The detrimental effects of these adversities may result in elevated risk of mortality in midlife and old age.

Objective

We investigate how combinations of these three ELAs affect later-life mortality and the life-course mediators that explain the associations.

Method

Data come from the first two waves of the Midlife in the United States (MIDUS) study and mortality records over a 20-year period (1995/96-2015). We used latent class analysis (LCA) to identify patterns of ELAs across the three domains and incorporated four life-course mediators: material, psychological, social resources, healthy lifestyle and substanc

SUBMITTER: Lee C 

PROVIDER: S-EPMC6894498 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature