Effect of Aortic Valve Disease on 3D Hemodynamics in Patients With Aortic Dilation and Trileaflet Aortic Valve Morphology.

ABSTRACT:

Background

The effect of different expressions of aortic valve disease on 3D aortic hemodynamics is unclear.

Purpose

To investigate changes in aortic hemodynamics in patients with dilated ascending aorta (AAo) but different severity of aortic valve stenosis (AS) and/or regurgitation (AR).

Study type

Retrospective.

Population

A total of 111 subjects (86 patients with AAo diameter ≥ 40 mm and 25 healthy controls, all with trileaflet aortic valve [TAV]). Patients were further stratified by TAV dysfunction: n = 9 with combined moderate or severe AS and AR (ASR, 56 ± 13 years), n = 14 with moderate or severe AS (AS, 64 ± 14 years), n = 33 with moderate or severe AR (AR, 62 ± 14 years), n = 30 with neither AS nor AR (no AS/AR, 63 ± 9 years).

Field strength/sequenc

SUBMITTER: Suwa K 

PROVIDER: S-EPMC6895394 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature