A pilot study of Livin gene and Yes-associated protein 1 expression in hepatocellular carcinoma patients.

ABSTRACT:

Background

Livin gene and Yes-Associated Protein 1 (YAP1 (play a pivotal role in organ size control and tumorigenesis.

Aim

In the present pilot study, we investigate the expression of Livin gene and YAP1 in hepatitis C virus (HCV) associated hepatocellular carcinoma (HCC) compared to other HCV patients and controls.Methods: the studied patients were divided into three groups 30 patients in each group in addition to 30 healthy subjects as a control group. Relative quantification of Livin gene and YAP-1 were assessed by quantitative Real Time RT-PCR (qPCR) in all studied patients and healthy controls. other laboratory investigations were done including complete blood count (CBC),international normalized ratio (INR) as well as liver function tests an

SUBMITTER: Badr EA 

PROVIDER: S-EPMC6895689 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature