CausalTAB: the PSI-MITAB 2.8 updated format for signalling data representation and dissemination.

ABSTRACT:

Motivation

Combining multiple layers of information underlying biological complexity into a structured framework represent a challenge in systems biology. A key task is the formalization of such information in models describing how biological entities interact to mediate the response to external and internal signals. Several databases with signalling information, focus on capturing, organizing and displaying signalling interactions by representing them as binary, causal relationships between biological entities. The curation efforts that build these individual databases demand a concerted effort to ensure interoperability among resources.

Results

Aware of the enormous benefits of standardization efforts in the molecular interaction research field, representatives of the sign

SUBMITTER: Perfetto L 

PROVIDER: S-EPMC6896241 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature