Epidemiology and prognosis of anti-infective therapy in the ICU setting during acute pancreatitis: a cohort study.

ABSTRACT: BACKGROUND:Recent international guidelines for acute pancreatitis (AP) recommend limiting anti-infective therapy (AIT) to cases of suspected necrotizing AP or nosocomial extrapancreatic infection. Limited data are available concerning empirical and documented AIT prescribing practices in patients admitted to the intensive care unit (ICU) for the management of AP. METHODS:Using a multicentre, retrospective (2009-2014), observational database of ICU patients admitted for AP, our primary objective was to assess the incidence of AIT prescribing practices during the first 30 days following admission. Secondary objectives were to assess the independent impact of centre characteristics on the incidence of AIT and to identify factors associated with crude hospital mortality in a logistic regressio

SUBMITTER: Montravers P 

PROVIDER: S-EPMC6896276 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature