Antibiotic regimens for neonatal sepsis - a protocol for a systematic review with meta-analysis.

ABSTRACT: BACKGROUND:Sepsis is a major cause of morbidity and mortality among neonates and infants. Antibiotics are a central part of the first line treatment for sepsis in neonatal intensive care units worldwide. However, the evidence on the clinical effects of the commonly used antibiotic regimens for sepsis in neonates remains scarce. This systematic review aims to assess the efficacy and harms of antibiotic regimens for neonatal sepsis. METHODS:Electronic searches will be conducted in MEDLINE, Embase, The Cochrane Library, CINAHL, ZETOC and clinical trial registries (clinicaltrials.gov and ISRCTN). We will include randomised controlled trials of different antibiotic regimens for sepsis of neonates and infants. Eligible interventions will be any antibiotic regimen. Two reviewers will independentl

SUBMITTER: Korang SK 

PROVIDER: S-EPMC6896287 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature