Transcriptional profiling of skeletal muscle reveals starvation response and compensatory growth in Spinibarbus hollandi.

ABSTRACT:

Background

Spinibarbus hollandi is an economically important fish species in southern China. This fish is known to have nutritional and medicinal properties; however, its farming is limited by its slow growth rate. In the present study, we observed that a compensatory growth phenomenon could be induced by adequate refeeding following 7 days of fasting in S. hollandi. To understand the starvation response and compensatory growth mechanisms in this fish, the muscle transcriptomes of S. hollandi under control, fasting, and refeeding conditions were profiled using next-generation sequencing (NGS) techniques.

Results

More than 4.45 × 10⁸ quality-filtered 150-base-pair Illumina reads were obtained from all nine muscle samples. De novo assemblies yielded a total of 156,7

SUBMITTER: Yang Y 

PROVIDER: S-EPMC6896686 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature