Flexitrate regional citrate anticoagulation in continuous venovenous hemodiafiltration: a retrospective analysis.

ABSTRACT: BACKGROUND:Flexitrate, an innovative regional citrate anticoagulation (RCA) protocol, was compared to traditional RCA (tRCA) and Heparin anticoagulation protocols in intensive care patients treated with continuous renal replacement therapy (CRRT). METHODS:A single-center, retrospective, cohort study, was done in a 26-bed intensive care unit in a large community hospital. Eighty dialysis sessions (Flexitrate?=?2852?h, tRCA?=?3580?h and Heparin?=?2026?h), performed in 53 patients, were evaluated for filter life, RCA control, and metabolic control. RESULTS:In the Flexitrate cohort, 3.8% of filters clotted, compared to 16.9% with tRCA and 28.3% with Heparin (p 

SUBMITTER: Lenga I 

PROVIDER: S-EPMC6896713 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature