Stratified reconstruction of ancestral Escherichia coli diversification.

ABSTRACT:

Background

Phylogenetic analyses of the bacterial genomes based on the simple classification in core- genes and accessory genes pools could offer an incomplete view of the evolutionary processes, of which some are still unresolved. A combined strategy based on stratified phylogeny and ancient molecular polymorphisms is proposed to infer detailed evolutionary reconstructions by using a large number of whole genomes. This strategy, based on the highest number of genomes available in public databases, was evaluated for improving knowledge of the ancient diversification of E. coli. This staggered evolutionary scenario was also used to investigate whether the diversification of the ancient E. coli lineages could be associated with particular lifestyles and adaptive strategies.

Result

SUBMITTER: Gonzalez-Alba JM 

PROVIDER: S-EPMC6896753 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature