Obstructive sleep apnea: Is it a biomarker of metabolic health in obesity.

ABSTRACT:

Context

The prevalence of obstructive sleep apnea (OSA) increases with obesity, and OSA has been linked to increased cardiovascular risk via hypoxemia and sleep disruption.

Objective and main outcome measures

We hypothesized that if OSA contributes to cardio-metabolic risk, then 1) obese individuals with OSA will have more cardio-metabolic disease, and 2) patients with OSA who are non-adherent to CPAP treatment will have a greater incidence of cardio-metabolic abnormalities.

Design setting and patients

We prospectively recruited obese patients (n = 83; BMI 49 ± 9 kg/m²). All patients had polysomnography and were stratified by 1) the absence/presence of OSA, and 2) metabolic health. Detailed CPAP reports were analyzed for compliance and OSA severity in 38 su

SUBMITTER: Becerra NLM 

PROVIDER: S-EPMC6897489 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature