Association between daptomycin susceptibility and teicoplanin resistance in Staphylococcus epidermidis.

ABSTRACT: Staphylococcus epidermidis infections are a common occurrence in hospitals, particularly in catheter-related bloodstream and surgical site infections and infective endocarditis. Higher daptomycin minimum inhibitory concentration (MIC) values may be associated with daptomycin treatment failure among patients with S. epidermidis infections. We therefore conducted a retrospective cohort study to determine the predictive value of daptomycin susceptibility. A retrospective study was undertaken in 1,337 patients with S. epidermidis infections. Data were collected from 1 January 2013 to 31 December 2016 at Ehime University Hospital, and included the following clinicopathological factors for evaluation: age, sex, resistance to vancomycin or teicoplanin, and history of antimicrobial therapy. Multip

SUBMITTER: Watanabe S 

PROVIDER: S-EPMC6898446 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature