Chromosome-level genome assembly for giant panda provides novel insights into Carnivora chromosome evolution.

ABSTRACT:

Background

Chromosome evolution is an important driver of speciation and species evolution. Previous studies have detected chromosome rearrangement events among different Carnivora species using chromosome painting strategies. However, few of these studies have focused on chromosome evolution at a nucleotide resolution due to the limited availability of chromosome-level Carnivora genomes. Although the de novo genome assembly of the giant panda is available, current short read-based assemblies are limited to moderately sized scaffolds, making the study of chromosome evolution difficult.

Results

Here, we present a chromosome-level giant panda draft genome with a total size of 2.29 Gb. Based on the giant panda genome and published chromosome-level dog and cat genomes, we conduc

SUBMITTER: Fan H 

PROVIDER: S-EPMC6898958 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature