Orthogonal Nanoparticle Catalysis with Organogermanes.

ABSTRACT: Although nanoparticles are widely used as catalysts, little is known about their potential ability to trigger privileged transformations as compared to homogeneous molecular or bulk heterogeneous catalysts. We herein demonstrate (and rationalize) that nanoparticles display orthogonal reactivity to molecular catalysts in the cross-coupling of aryl halides with aryl germanes. While the aryl germanes are unreactive in L_n Pd⁰ /L_n Pd^II catalysis and allow selective functionalization of established coupling partners in their presence, they display superior reactivity under Pd nanoparticle conditions, outcompeting established coupling partners (such as ArBPin and ArBMIDA) and allowing air-tolerant, base-free, and orthogonal access to valuable and challe

SUBMITTER: Fricke C 

PROVIDER: S-EPMC6899604 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature