Ten-year evolution of a massive transfusion protocol in a level 1 trauma centre: have outcomes improved?

ABSTRACT: BACKGROUND:We aimed to evaluate the evolution and implementation of the massive transfusion protocol (MTP) in an urban level 1 trauma centre. Most data on this topic comes from trauma centres with high exposure to life-threatening haemorrhage. This study examines the effect of the introduction of an MTP in an Australian level 1 trauma centre. METHODS:A retrospective study of prospectively collected data was performed over a 14-year period. Three groups of trauma patients, who received more than 10 units of packed red blood cells (PRBC), were compared: a pre-MTP group (2002-2006), an MTP-I group (2006-2010) and an MTP-II group (2010-2016) when the protocol was updated. Key outcomes were mortality, complications and number of blood products transfused. RESULTS:A total of 168 patients were in

SUBMITTER: van der Meij JE 

PROVIDER: S-EPMC6899724 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature