The validity of the viscero-abdominal disproportion ratio for type of surgical closure in all fetuses with an omphalocele.

ABSTRACT:

Objective

To determine the predictive value of the fetal omphalocele circumference/abdominal circumference (OC/AC) ratio for type of surgical closure and survival and to describe the trajectory of OC/AC ratio throughout gestation.

Methods

This cohort study included all live-born infants prenatally diagnosed with an omphalocele in our tertiary centre (2000-2017) with an intention to treat. The OC/AC ratio and liver position were determined using 2D ultrasound at three periods during gestation (11-16, 17-26, and/or 30-38 weeks). Primary outcome was type of closure; secondary outcome was survival. In the secondary analyses, the predictive value of the OC/AC-ratio trend for type of closure and survival was assessed.

Results

Primary closure was performed in 37/63 (59%) inf

SUBMITTER: Peters NCJ 

PROVIDER: S-EPMC6899735 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature