Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide.

ABSTRACT:

Background

Atopic dermatitis (AD) is a heterogeneous disease with a multifactorial aetiology and complex pathophysiology. This heterogeneity translates into different trajectories of disease progression with respect to severity, persistence and risk of development of atopic comorbidities. Determining which possible disease trajectories or comorbidities any individual child might develop is challenging in clinical practice. Tools that help identify paediatric patients at higher risk of disease progression would greatly aid clinicians.

Methods

We reviewed recent cohort studies to synthesize and simplify the epidemiological data to try to identify shared clinically relevant characteristics that may help physicians estimate the risk of disease progression in paediatric patients

SUBMITTER: Irvine AD 

PROVIDER: S-EPMC6899789 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature