Analysis of Mortality among Neonates and Children with Spina Bifida: An International Registry-Based Study, 2001-2012.

ABSTRACT:

Background

Medical advancements have resulted in better survival and life expectancy among those with spina bifida, but a significantly increased risk of perinatal and postnatal mortality for individuals with spina bifida remains.

Objectives

To examine stillbirth and infant and child mortality among those affected by spina bifida using data from multiple countries.

Methods

We conducted an observational study, using data from 24 population- and hospital-based surveillance registries in 18 countries contributing as members of the International Clearinghouse for Birth Defects Surveillance and Research (ICBDSR). Cases of spina bifida that resulted in livebirths or stillbirths from 20 weeks' gestation or elective termination of pregnancy for fetal anomaly (ETOPFA) were inc

SUBMITTER: Bakker MK 

PROVIDER: S-EPMC6899817 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature