Project description:This study evaluates the gene expression patterns in 36 decidual samples of women having gone through different types of child birth. The samples were profiled on Illumina Human HT-12_v4 BeadArrays. The analysis includes quality control and exploratory analysis of the dataset, followed by the identification of differentially expressed genes (DEGs) and finally, functional analysis for enrichment of KEGG pathways and GO terms amongst the DEGs. The statistical analysis was performed for six comparisons: Term labour (TL) vs Term not labour (TNL), TL vs Preterm labour (PTL), TL vs Preterm non-labour (PTNL), TNL vs PTL, TNL vs PTNL and PTL vs PTNL. This study evaluates the gene expression levels from decidual samples obtained from women giving birth with different types of labour. The dataset was composed of 36 Illumina Human HT-12_v4 expression BeadArrays.

2017-08-23 | E-MTAB-5353 | biostudies-arrayexpress

Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial.

Project description: Not available

| S-EPMC6939660 | biostudies-literature

RNA-seq transcriptomes of term not in labour and term in labour human myometrial tissue

Project description:Purpose: To chart the human myometrial transcriptomes before and after the onset of labour. Methods: Tophat splice junction mapping of paired-end reads, HTSeq to generate counts, cufflinks to track transcripts, DESeq, edgeR and baySeq to detect differentially expressed genes and principal component analysis for clustering analyses. Results: We mapped on average 14 million paired-end reads per sample (counting each end individually) to the human genome (build hg19) and covered the expressed transcriptome about 13 times with a TopHat-HTSeq workflow. We performed a comparative analysis with an analogous microarray study (Mittal et al., 2010) and found some overlap between the RNA-seq and the microarray data. Conclusions: Our study is the first RNA-seq study of the human myometrium before and after the onset of labour. We show that while microarray and RNA-seq studies may complement each other, RNA-seq has a much greater resolution.

2014-02-17 | GSE50599 | GEO

RNA-seq transcriptomes of term not in labour and term in labour human myometrial tissue

2014-02-17 | E-GEOD-50599 | biostudies-arrayexpress

Intrapartum interventions and outcomes for women and children following induction of labour at term in uncomplicated pregnancies: a 16-year population-based linked data study.

Project description: Not available

| S-EPMC8169493 | biostudies-literature

Experience of induction of labour: a cross-sectional postnatal survey of women at UK maternity units.

Project description: Not available

| S-EPMC10174017 | biostudies-literature

Lived experiences of women during induction of labour at a tertiary hospital in Ghana: A qualitative study.

Project description: Not available

| S-EPMC10868737 | biostudies-literature