Reversible Covalent End-Capping of Collagen Model Peptides.

ABSTRACT: The combination of supramolecular aggregation of collagen model peptides with reversible covalent end-capping of the formed triple helix in a single experimental set-up yielded minicollagens, which were characterized by a single melting temperature. In spite of the numerous possible reaction intermediates, a specific synthetic collagen with a leading, middle and trailing strand is formed in a highly cooperative self-assembly process.

SUBMITTER: Priem C 

PROVIDER: S-EPMC6900188 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature