Validity of bispectral index monitoring during deep sedation in children with spastic cerebral palsy undergoing injection of botulinum toxin.

ABSTRACT:

Background

This prospective study aimed to determine whether the bispectral index (BIS) is a valid objective tool for differentiating adequate from inadequate deep sedation in spontaneously breathing children with cerebral palsy (CP).

Methods

Propofol was titrated to increase the level of sedation with a continuous infusion of remifentanil at a rate of 0.05 μg/kg/min while maintaining spontaneous ventilation in 22 children with spastic CP, aged 3-18 years. The depth of sedation was assessed using the University of Michigan Sedation Scale (UMSS) and the Modified Observer's Assessment of Alertness and Sedation (MOAAS) scale. Receiver operating characteristic curve analysis was performed to determine the cutoff BIS values for deep sedation, defined as a UMSS score of 3-4 and a

SUBMITTER: Jung SM 

PROVIDER: S-EPMC6900421 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature