Prenatal oxidative balance and risk of asthma and allergic disease in adolescence.

ABSTRACT:

Background

Fetal oxidative balance (achieved when protective prenatal factors counteract sources of oxidative stress) might be critical for preventing asthma and allergic disease.

Objective

We examined prenatal intakes of hypothesized protective nutrients (including antioxidants) in conjunction with potential sources of oxidative stress in models of adolescent asthma and allergic disease.

Methods

We used data from 996 mother-child pairs in Project Viva. Exposures of interest were maternal prepregnancy body mass index and prenatal nutrients (energy-adjusted intakes of vitamins D, C, and E; β-carotene; folate; choline; and n-3 and n-6 polyunsaturated fatty acids [PUFAs]), air pollutant exposures (residence-specific third-trimester black carbon or particulate matter with

SUBMITTER: Sordillo JE 

PROVIDER: S-EPMC6900442 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature