Association of aortic vascular uptake of ¹⁸FDG by PET/CT and aortic wall thickness by MRI in psoriasis: a prospective observational study.

ABSTRACT:

Background

The contribution of inflammation to the incidence of cardiovascular disease (CVD) has been increasingly recognized in recent years. We investigated the relationship of aortic vascular uptake of 18F-FDG by PET/CT and aortic wall thickness (AWT) by MRI in psoriasis, a chronic inflammatory disease with increased incidence of CVD. One hundred sixty-five patients with plaque psoriasis participated in an ongoing longitudinal cohort study. Subclinical atherosclerosis was assessed as aortic uptake of 18F-FDG by PET/CT reported as target-to-background ratio (TBR) and AWT by MRI reported as maximal thickness.

Results

Patients with psoriasis were middle aged, predominantly male, and had mild CV risk by traditional risk factors. Psoriasis severity as measured by PASI score wa

SUBMITTER: Groenendyk JW 

PROVIDER: S-EPMC6901110 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature