Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers.

ABSTRACT:

Importance

Few studies have investigated the association of long-term ambient ozone exposures with respiratory morbidity among individuals with a heavy smoking history.

Objective

To investigate the association of historical ozone exposure with risk of chronic obstructive pulmonary disease (COPD), computed tomography (CT) scan measures of respiratory disease, patient-reported outcomes, disease severity, and exacerbations in smokers with or at risk for COPD.

Design, setting, and participants

This multicenter cross-sectional study, conducted from November 1, 2010, to July 31, 2018, obtained data from the Air Pollution Study, an ancillary study of SPIROMICS (Subpopulations and Intermediate Outcome Measures in COPD Study). Data analyzed were from participants enrolled at 7

SUBMITTER: Paulin LM 

PROVIDER: S-EPMC6902160 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature