Mortality Among Referral Patients With Hypertrophic Cardiomyopathy vs the General European Population.

ABSTRACT:

Importance

It is unclear whether hypertrophic cardiomyopathy (HCM) conveys excess mortality when compared with the general population.

Objective

To compare the survival of patients with HCM with that of the general European population.

Design, setting, and participants

Retrospective cohort study of 4893 consecutive adult patients with HCM presenting at 7 European referral centers between 1980 and 2013. The data were analyzed between April 2018 and August 2019.

Main outcomes and measures

Survival was compared using standardized mortality ratios (SMRs) calculated with data from Eurostat, stratified by study period, country, sex, and age, and using a composite end point in the HCM cohort of all-cause mortality, aborted sudden cardiac death, and heart transplant.

SUBMITTER: Lorenzini M 

PROVIDER: S-EPMC6902239 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature