Glyoxalase 1 gene improves the antistress capacity and reduces the immune inflammatory response.

ABSTRACT: BACKGROUND:Fish immunity is not only affected by the innate immune pathways but is also triggered by stress. Transport and loading stress can induce oxidative stress and further activate the immune inflammatory response, which cause tissue damage and sudden death. Multiple genes take part in this process and some of these genes play a vital role in regulation of the immune inflammatory response and sudden death. Currently, the key genes regulating the immune inflammatory response and the sudden death caused by stress in Coilia nasus are unknown. RESULTS:In this study, we studied the effects of the Glo1 gene on stress, antioxidant expression, and immune-mediated apoptosis in C. nasus. The full-length gene is 4356 bp, containing six exons and five introns. Southern blotting indicated that Gl

SUBMITTER: Du F 

PROVIDER: S-EPMC6902355 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature