Initial therapy affects duration of diarrhoea in critically ill patients with Clostridioides difficile infection (CDI).

ABSTRACT:

Background

Critically ill patients in the intensive care unit (ICU) are at high risk for developing Clostridioides difficile infections (CDI). Risk factors predicting their mortality or standardized treatment recommendations have not been defined for this cohort. Our goal is to determine outcome and mortality associated risk factors for patients at the ICU with CDI by evaluating clinical characteristics and therapy regimens.

Methods

A retrospective single-centre cohort study. One hundred forty-four patients (0.4%) with CDI-associated diarrhoea were included (total 36.477 patients admitted to 12 ICUs from January 2010 to September 2015). Eight patients without specific antibiotic therapy were excluded, so 132 patients were analysed regarding mortality, associated risk factors

SUBMITTER: Manthey CF 

PROVIDER: S-EPMC6902451 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature