Dosimetric factors associated with long-term patient-reported outcomes after definitive radiotherapy of patients with head and neck cancer.

ABSTRACT: BACKGROUND:The aim of this study was to explore the relationships between dosimetric parameters of organs at risk and patient-reported outcomes (PRO) after radiotherapy of patients with head and neck cancer. METHODS:PRO data of 53 patients with head and neck cancer treated with radiotherapy were prospectively collected. These data concerned health-related quality of life (HRQOL) and were collected using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) and head and neck cancer module (QLQ-H&N35). Patients were divided into "severe-deterioration" and "mild-deterioration" groups on the basis of degree of deterioration HRQOL > 6 months after completing treatment. The relationships between HRQOL deteriorations and patient-related or dosimetr

SUBMITTER: Hayakawa T 

PROVIDER: S-EPMC6902539 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature