Association of age, sex and BMI with the rate of change in tibial cartilage volume: a 10.7-year longitudinal cohort study.

ABSTRACT: BACKGROUND:To describe the association of age, sex and body mass index with the rate of change of tibial knee cartilage volume over 10.7 years in a community-based sample of older adults. METHODS:Four hundred and eighty-one participants (49% female, mean age 60.8 years [range 51.1-79.7], 49% had knee pain and 58% radiographic osteoarthritis) were included. Tibial cartilage volume of the right knee was assessed on T1-weighted fat-suppressed 1.5 T MRI at baseline and 10.7 years. Data analyses were performed using linear regression models. RESULTS:The average rate of loss of cartilage volume was 1.2%/year (range 0.2-3.9%) with all participants losing cartilage volume over the study period. There was a significant association between age and loss of tibial cartilage volume in the medial (0.023

SUBMITTER: Cai G 

PROVIDER: S-EPMC6902563 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature