The Neuropeptide Hormone Oxytocin in Eating Disorders.

ABSTRACT:

Purpose of review

The neurohormone oxytocin (OXT) impacts food intake as well as cognitive, emotional, and social functioning-all of which are central to eating disorder (ED) pathology across the weight spectrum. Here, we review findings on endogenous OXT levels and their relationship to ED pathology, the impact of exogenous OXT on mechanisms that drive ED presentation and chronicity, and the potential role of genetic predispositions in the OXT-ED link.

Recent findings

Current findings suggest a role of the OXT system in the pathophysiology of anorexia nervosa. In individuals with bulimia nervosa, endogenous OXT levels were comparable to those of healthy controls, and exogenous OXT reduced food intake. Studies in other ED are lacking. However, genetic studies suggest a broad

SUBMITTER: Plessow F 

PROVIDER: S-EPMC6903388 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature