Sarcopenia and ovarian cancer survival: a systematic review and meta-analysis.

ABSTRACT:

Background

Sarcopenia is the loss of skeletal muscle mass and function that occurs with advancing age and certain diseases. It is thought to have a negative impact on survival in cancer patients. Routine computed tomography imaging is often used to quantify skeletal muscle in cancer patients. Sarcopenia is defined by a low skeletal muscle index (SMI). Skeletal muscle radiation attenuation (SMRA) is used to define muscle quality. The primary aim of this meta-analysis was to study the association between sarcopenia or SMRA and overall survival (OS) or complications in patients with ovarian cancer.

Methods

Medline, Embase, CINAHL, and PEDro databases were searched from inception to 15 February 2019. Studies evaluating the prognostic effect of SMI and SMRA on ovarian cancer surv

SUBMITTER: Ubachs J 

PROVIDER: S-EPMC6903439 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature