Aerobic Exercise Training Improves Cerebral Blood Flow and Executive Function: A Randomized, Controlled Cross-Over Trial in Sedentary Older Men.

ABSTRACT:

Background

Physical activity may attenuate age-related cognitive decline by improving cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic exercise training on cerebral blood flow (CBF), which is a sensitive physiological marker of cerebrovascular function, in sedentary older men.

Methods

Seventeen apparently healthy men, aged 60-70 years and with a BMI between 25 and 35 kg/m², were included in a randomized, controlled cross-over trial. Study participants were randomly allocated to a fully-supervised, progressive, aerobic exercise training or no-exercise control period for 8 weeks, separated by a 12-week wash-out period. Measurements at the end of each period included aerobic fitness evaluated using peak oxygen consumptio

SUBMITTER: Kleinloog JPD 

PROVIDER: S-EPMC6904365 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature