Association between fluoride exposure and cardiometabolic risk in peripubertal Mexican children.

ABSTRACT:

Background

Several animal studies have suggested that fluoride exposure may increase the levels of cardiometabolic risk factors, but little is known about whether fluoride exposure is associated with such risk in humans.

Objectives

We examined the cross-sectional association between peripubertal exposure to fluoride and markers of cardiometabolic risk in 280 girls and 256 boys at age 10-18 years living in Mexico City.

Methods

We measured plasma fluoride concentration using a microdiffusion method. We collected data on anthropometry including BMI, waist circumference (WC) and trunk fat percentage. We measured serum markers of cardiometabolic risk, including fasting glucose, insulin and lipids. All the indicators of outcome were converted to age- and sex-specific z-scor

SUBMITTER: Liu Y 

PROVIDER: S-EPMC6904509 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature