GaCl₃-Catalyzed Ring-Opening Carbonyl-Olefin Metathesis.

ABSTRACT: The development of a Lewis acid-catalyzed ring-opening cross-metathesis reaction which enables selective access to acyclic, unsaturated ketones as the carbonyl-olefin metathesis products is described. While catalytic amounts of FeCl₃ were previously identified as optimal to catalyze ring-closing metathesis reactions, the complementary ring-opening metathesis between cyclic alkenes and carbonyl functionalities relies on GaCl₃ as the superior Lewis acid catalyst.

SUBMITTER: Albright H 

PROVIDER: S-EPMC6905395 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature