Loading the dice: The orientation of virus-like particles adsorbed on titanate assisted organosilanized surfaces.

ABSTRACT: The organization of virus-like particles (VLPs) on surfaces is a relevant matter for both fundamental and biomedical sciences. In this work, the authors have tailored surfaces with different surface tension components aiming at finding a relationship with the affinity of the different geometric/surface features of icosahedral P22 VLPs. The surfaces have been prepared by titanate assisted organosilanization with glycidyloxy, amino, and perfluoro silanes. Vibrational and photoelectron spectroscopies have allowed identifying the different functional groups of the organosilanes on the surfaces. Atomic force microscopy (AFM) showed that, irrespective of the organosilane used, the final root mean square roughness remains below 1 nm. Contact angle analyses confirm the effective formation of a set

SUBMITTER: Moreno-Cerrada D 

PROVIDER: S-EPMC6905651 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature