Ontology highlight
ABSTRACT:
SUBMITTER: Giobbe GG
PROVIDER: S-EPMC6906306 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Nature communications 20191211 1
Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. However, their clinical application is greatly limited by the lack of effective GMP-compliant systems for organoid expansion in culture. Here, we envisage that the use of extracellular matrix (ECM) hydrogels derived from decellularized tissues (DT) can provide an environment capable of directing cell growth. These gels possess the biochemical signature of tissue-specific ECM a ...[more]