Delineating the cognitive-neural substrates of writing: a large scale behavioral and voxel based morphometry study.

ABSTRACT: The current study investigated the cognitive and neural substrates that underpin writing ability. We explored similarities and differences in writing numbers and words and compared these to language and manual actions in a large group of sub-acute, stroke patients (n = 740). The behavioral data showed association and dissociation in the ability to write words and numbers. Comorbidities of writing deficits with both language and motor impairments were prevalent, with less than a handful showing deficits restricted to the writing tasks. A second analysis with a subset of patients (n = 267) explored the neural networks that mediate writing abilities. Lesion to right temporal contributed to writing words, while lesions to left postcentral contributed to writing numbers. Overlapping neural mech

SUBMITTER: Chen H 

PROVIDER: S-EPMC6906401 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature