Aberrant functional connectivity of resting state networks related to misperceptions and intra-individual variability in Parkinson's disease.

ABSTRACT: Patients with Parkinson's disease (PD) frequently suffer from visual misperceptions and hallucinations, which are difficult to objectify and quantify. We aimed to develop an image recognition task to objectify misperceptions and to assess performance fluctuations in PD patients with and without self-reported hallucinations. Thirty-two non-demented patients with Parkinson's disease (16 with and 16 without self-reported visual hallucinations) and 25 age-matched healthy controls (HC) were tested. Participants performed a dynamic image recognition task with real and scrambled images. We assessed misperception scores and intra-individual variability in recognition times. To gain insight into possible neural mechanisms related to misperceptions and performance fluctuations we correlated resting

SUBMITTER: Miloserdov K 

PROVIDER: S-EPMC6906716 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature