Estimation of Sialic Acid and IL10 Levels in Stage 1 and 2 Periodontitis Patients.

ABSTRACT:

Objective

The role of biomarkers in staging and grading periodontal disease has become detrimental in relation to the overall treatment plan. This study aimed at evaluating and comparing the role of sialic acid and IL10 in the early and moderate stages of periodontitis.

Materials and methods

Patients were selected according to the assessment of pocket depth and radiographic bone loss. Bone loss was calculated as <15% for stage 1 and 15-33% for stage 2. Salivary samples were collected using spit technique 2 hrs post consumption of food. The unstimulated saliva was collected in a sterile graduated container every minute for 5-8 minutes. IL10 estimation was done using ELISA, and sialic acid estimation was done using the diphenylamine method. The variables for the three groups w

SUBMITTER: Varma SR 

PROVIDER: S-EPMC6906883 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature