Economic evaluation of HPV DNA test as primary screening method for cervical cancer: A health policy discussion in Greece.

ABSTRACT: BACKGROUND:HPV test appears to be more effective in cervical cancer (CC) screening. However, the decision of its adoption as a primary screening method by substituting the established cytology lies in the evaluation of multiple criteria. Aim of this study is to evaluate the economic and clinical impact of HPV test as primary screening method for CC. METHODS:A decision tree and a Markov model were developed to simulate the screening algorithm and the natural history of CC. Fourteen different screening strategies were evaluated, for women 25-65 years old. Clinical inputs were drawn from the HERMES study and cost inputs from the official price lists. In the absence of CC treatment cost data, the respective Spanish costs were used after being converted to 2017 Greek values. One-way and probabi

SUBMITTER: Skroumpelos A 

PROVIDER: S-EPMC6907825 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature