Determining the post-elimination level of vaccination needed to prevent re-establishment of dog rabies.

ABSTRACT:

Background

Once a canine rabies-free status has been achieved, there is little guidance available on vaccination standards to maintain that status. In areas with risk of reintroduction, it may be practical to continue vaccinating portions of susceptible dogs to prevent re-establishment of canine rabies.

Methods

We used a modified version of RabiesEcon, a deterministic mathematical model, to evaluate the potential impacts and cost-effectiveness of preventing the reintroduction of canine rabies through proactive dog vaccination. We analyzed four scenarios to simulate varying risk levels involving the reintroduction of canine rabies into an area where it is no longer present. In a sensitivity analysis, we examined the influences of reintroduction frequency and intensity, the de

SUBMITTER: Jeon S 

PROVIDER: S-EPMC6907870 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature