Asymmetrical diversification of the receptor-ligand interaction controlling self-incompatibility in Arabidopsis.

ABSTRACT: How two-component genetic systems accumulate evolutionary novelty and diversify in the course of evolution is a fundamental problem in evolutionary systems biology. In the Brassicaceae, self-incompatibility (SI) is a spectacular example of a diversified allelic series in which numerous highly diverged receptor-ligand combinations are segregating in natural populations. However, the evolutionary mechanisms by which new SI specificities arise have remained elusive. Using in planta ancestral protein reconstruction, we demonstrate that two allelic variants segregating as distinct receptor-ligand combinations diverged through an asymmetrical process whereby one variant has retained the same recognition specificity as their (now extinct) putative ancestor, while the other has functionally diverg

SUBMITTER: Chantreau M 

PROVIDER: S-EPMC6908432 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature